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Nuclear receptor cross-talk
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Patrick Maurel, PhD Inserm U632, University Montpellier-1 EA3768 CNRS Campus, 1919, route de Mende 34293 Montpellier (Cedex 05) France |
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The research program
developped at Inserm U632 focuses on three main themes: hepatic
detoxication, hepatitis C virus infection (HCV) and liver stem cells.
The work is based on the original methodology of primary cultures of
human
hepatocytes, and combines both basic and clinical research. Key words: human hepatocyte culture, cytochrome P450 (CYP), gene regulation, nuclear receptors PXR and CAR, metabolism and side effects of drugs, replication of hepatis C virus, liver stem cell, embryonic stem cell, differentiation Inserm U632 is part of the Federative Research Institute (IFR122): Cell Biology, Molecular Genetics, Infectious Processes and Pharmacology, and is affiliated to the Biotherapy Research Institute (IRB). |
Date of last modification: December 9 2009